State Ledger
Company profile

Septerna, Inc. CIK 1984086

Ticker
SEPN (Nasdaq)
Industry
Pharmaceutical Preparations
Headquarters
South San Francisco, CA 94080
Fiscal year end
2025 (FY)
Market Data
Close
$36.33
Change
-$1.22
Change %
-3.25%
Volume
17,001

SEPN · trading date Oct 13, 2026 · previous close $37.55 · source: Alpaca (IEX feed, not consolidated full-market data).

Key Financials
Revenue
$45.95M
Net income
-$48.88M
Total assets
$596.19M
Total liabilities
$214.26M
Stockholders' equity
$381.93M
Cash & equivalents
$120.72M
Operating income
-$68.30M
Operating cash flow
$110.19M
Capital expenditures
$518.0K

Fiscal year 2025, via 10-K filed 2026-03-09. A dash means this figure wasn't reported in the source filing under a field State Ledger recognizes - not that the value is zero.

Financial Performance
Operating margin
-148.6%
Net margin
-106.4%
Free cash flow
$109.67M
Free cash flow margin
238.7%
Liabilities / assets
35.9%
Equity / assets
64.1%
CapEx / revenue
1.1%
Operating cash flow / net income
-2.25×

Derived from the fiscal year 2025 figures above. These metrics are mathematical calculations and do not represent a rating or assessment of the company.

Financial History
Fiscal yearRevenueNet incomeAssetsLiabilitiesEquity
2025 $45.95M -$48.88M $596.19M $214.26M $381.93M
2024 $1.08M -$71.80M $456.55M $36.51M $420.05M
2023 $151.0K $4.18M $130.87M $20.03M -$38.37M
Company Details
SIC code
2834
State of incorporation
DE
Active filer
Yes
Most recent SEC filing
Form 4
2026-09-10
Financials filed via
Form 10-K
filed 2026-03-09

"Most recent SEC filing" may differ from the filing used for the financial figures above.

Location
South San Francisco, CA 94080
250 EAST GRAND AVENUE, SUITE 65
Data & Methodology

SEC EDGAR submissions API (identity, collected Sep 19, 2026, 15:11 UTC) and SEC XBRL Company Facts API (financials, collected Sep 26, 2026, 15:20 UTC) · figures as originally filed, not restated · a dash always means a value wasn't reported, never a real zero.

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