State Ledger
Company profile

Spero Therapeutics, Inc. CIK 1701108

Ticker
SPRO (Nasdaq)
Industry
Pharmaceutical Preparations
Headquarters
Cambridge, MA 02139
Fiscal year end
2025 (FY)
Market Data
Close
$1.11
Change
-$0.05
Change %
-3.90%
Volume
45,831

SPRO · trading date Oct 14, 2026 · previous close $1.16 · source: Alpaca (IEX feed, not consolidated full-market data).

Key Financials
Revenue
$66.80M
Net income
$8.57M
Total assets
$68.92M
Total liabilities
$9.90M
Stockholders' equity
$59.02M
Cash & equivalents
$40.27M
Operating income
$6.31M
Operating cash flow
-$12.62M
Capital expenditures
—

Fiscal year 2025, via 10-K filed 2026-03-26. A dash means this figure wasn't reported in the source filing under a field State Ledger recognizes - not that the value is zero.

Financial Performance
Operating margin
9.5%
Net margin
12.8%
Free cash flow
—
Free cash flow margin
—
Liabilities / assets
14.4%
Equity / assets
85.6%
CapEx / revenue
—
Operating cash flow / net income
-1.47×

Derived from the fiscal year 2025 figures above. These metrics are mathematical calculations and do not represent a rating or assessment of the company.

Financial History
Fiscal yearRevenueNet incomeAssetsLiabilitiesEquity
2025 $66.80M $8.57M $68.92M $9.90M $59.02M
2024 $47.98M -$68.57M $110.54M $64.42M $46.12M
2023 $103.78M $22.81M $182.39M $75.50M $106.89M
2022 $53.51M $46.42M $124.80M $48.87M $75.93M
2021 $18.26M -$89.80M $171.07M $82.78M $88.29M
Company Details
SIC code
2834
State of incorporation
DE
Active filer
Yes
Most recent SEC filing
Form EFFECT
2026-09-10
Financials filed via
Form 10-K
filed 2026-03-26

"Most recent SEC filing" may differ from the filing used for the financial figures above.

Location
Cambridge, MA 02139
675 MASSACHUSETTS AVENUE
Data & Methodology

SEC EDGAR submissions API (identity, collected Sep 19, 2026, 15:11 UTC) and SEC XBRL Company Facts API (financials, collected Sep 26, 2026, 15:34 UTC) · figures as originally filed, not restated · a dash always means a value wasn't reported, never a real zero.

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