State Ledger
Company profile

Karyopharm Therapeutics Inc. CIK 1503802

Ticker
KPTI (Nasdaq)
Industry
Pharmaceutical Preparations
Headquarters
Newton, MA 02459
Fiscal year end
2025 (FY)
Market Data
Close
$0.50
Change
-$0.09
Change %
-15.11%
Volume
11,939

KPTI · trading date Oct 12, 2026 · previous close $0.59 · source: Alpaca (IEX feed, not consolidated full-market data).

Key Financials
Revenue
$146.07M
Net income
-$196.04M
Total assets
$108.42M
Total liabilities
$401.34M
Stockholders' equity
-$292.93M
Cash & equivalents
$60.54M
Operating income
-$90.71M
Operating cash flow
-$75.37M
Capital expenditures
$0

Fiscal year 2025, via 10-K filed 2026-02-13. A dash means this figure wasn't reported in the source filing under a field State Ledger recognizes - not that the value is zero.

Financial Performance
Operating margin
-62.1%
Net margin
-134.2%
Free cash flow
-$75.37M
Free cash flow margin
-51.6%
Liabilities / assets
370.2%
Equity / assets
-270.2%
CapEx / revenue
0.0%
Operating cash flow / net income
0.38×

Derived from the fiscal year 2025 figures above. These metrics are mathematical calculations and do not represent a rating or assessment of the company.

Financial History
Fiscal yearRevenueNet incomeAssetsLiabilitiesEquity
2025 $146.07M -$196.04M $108.42M $401.34M -$292.93M
2024 $145.24M -$76.42M $164.42M $350.44M -$186.02M
2023 $146.03M -$143.10M $240.44M $376.64M -$136.21M
2022 $157.07M -$165.29M $358.17M $374.83M -$16.66M
2021 $209.82M -$124.09M $305.31M $384.98M -$79.67M
Company Details
SIC code
2834
State of incorporation
DE
Active filer
Yes
Most recent SEC filing
Form 8-K
2026-09-18
Financials filed via
Form 10-K
filed 2026-02-13

"Most recent SEC filing" may differ from the filing used for the financial figures above.

Location
Newton, MA 02459
85 WELLS AVENUE
Data & Methodology

SEC EDGAR submissions API (identity, collected Sep 19, 2026, 15:11 UTC) and SEC XBRL Company Facts API (financials, collected Sep 26, 2026, 15:34 UTC) · figures as originally filed, not restated · a dash always means a value wasn't reported, never a real zero.

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